Revivelife Clinic I Naturopath in Ottawa

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iv max-PAIN & INFLAMMATION

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  • Restores Nutrients
  • Reduces Pain & Inflammation
  • Supports Healing

HELPS

  • Injuries
  • Athletic Performance
  • Fibromyalgia
  • Arthritis

FREQUENCY

  • Tailored to you. Commonly once a week until therapeutic results are obtained (4-8 treatments)
  • Reassessment and then maintenance monthly.

IV therapy with high dose magnesium, B vitamins and vitamin C has been found to help reduce pain and inflammation, improve energy and overall wellness in those with chronic pain including those with back pain, fibromyalgia, arthritis, injuries, headaches and migraines.1-5

HOW DOES THE IV MAX- PAIN & INFLAMMATION WORK?

IV Pain Relax works to reduce pain due to a variety of causes. Pain can be divided into two main broad classes nociceptive and neuropathic.6-8 Nociceptive pain results from activation of peripheral pain receptors and includes sprains, fractures, osteoarthritis, arthritis, and myofascial pain.6-8 Neuropathic pain results from an injury or dysfunction to the nervous system and is often described as burning, crushing, and “pins and needles”) and includes post-shingles neuralgia, nerve trauma, and carpal tunnel syndrome.6-8  Nociceptive pain is linked to inflammation while neuropathic pain may be more difficult to treat9 Several studies have suggested that free radicals play a role in exaggerated pain hypersensitivity and thus antioxidants are helpful for pain management strategies.10

faqs

Ingredients: B Vitamins, Vitamin B5, Vitamin B6, Biotin, Vitamin C, Calcium, Magnesium, Taurine, Selenium, Zinc

  • B Vitamins such as B1, B6, and B12 have been proven to be clinically effective in treating various nociceptive and neurogenic painful conditions such as sciatica, degenerative spine disease, rheumatic diseases, low-back pain, trigeminal neuralgia, facial paralysis, and optic neuritis as acting as a pain reliever.11-14
  • Vitamin B5 decreases the release of myeloperoxidase from granulocytes and inhibits the formation of free oxygen radicals, and it exhibits an anti-inflammatory effect by increasing mitotic activity.
  • Vitamin B6 has antioxidant and anti-inflammatory properties.
  • Biotin helps to reduce inflammation in the body.
  • Vitamin C is an antioxidant that has been linked to rapid and consistent ability to help to reduce inflammation, and nociceptive pain in animal studies.15,16 Prophylactic vitamin C has also been linked to a 5-fold decrease in the incidence of complex regional pain syndrome amount patients who recently underwent foot/ankle surgery compared to no treatment17
  • Calcium helps to relax spasms in muscles to help reduce pain
  • Magnesium: reduces nerve pain, and helps to calm the nervous system by modulating the excitatory-to-inhibitory actions of GABA and glutamate in the brain, respectively.18,19
  • Taurine boosts circulation and inter-cellular energy—helping with rehydration; to  promote healing.
  • Selenium helps protect the body from mitochondrial oxidative stress which is important to help reduce pain.20
  • Zinc helps to reduce pain, supports immunity, and the adrenal gland.21

Note – formulas may be modified occasionally

OPTIONAL ADD ONS

  • IM Fuel D: Vitamin D metabolites help reduce inflammation by regulating cytokines and deficiency is linked to several painful conditions30,31
  • IV Fuel G Push: Gluathione is the body’s master antioxidant and reduces free radical damage to help manage pain.32

This mini formula contains magnesium and B vitamins to help reduce pain.

Ingredients: B Vitamins, MethylB12, Magnesium, Glycine, Taurine

  1. Ellis FR, Nasser S. A pilot study of vitamin B12 in the treatment of tiredness. Br J Nutr 1973;30:277-283
  2. Lapp CW, Cheney PR. The rationale for using high-dose cobalamin (vitamin B12). CFIDS Chronicle Physicians’ Forum 1993 (Fall):1920.
  3. Massey PB. Reduction of fibromyalgia symptoms through intravenous nutrient therapy: results of a pilot clinical trial. Altern Ther Health Med. 2007 May-Jun;13(3):32-4.
  4. Ali, A; Njike, VY, et al. (2009). “Intravenous Micronutrient Therapy (Myers’ Cocktail) for Fibromyalgia: A Placebo-Controlled Pilot Study“. The Journal of Alternative and Complementary Medicine. 15 (3): 247–25.
  5. Mauskop A, Altura BT, Cracco RQ, Altura BM. Intravenous magnesium sulphate relieves migraine attacks in patients with low serum ionized magnesium levels: a pilot study. Clin Sci 1995;89:633-636.
  6. Cohen S., Raja S., Chapter 29 – Pain. In: Goldman: Goldman’s Cecil Medicine, 24th ed. Pg 133. Copyright © 2011 Saunders, An Imprint of Elsevier. Philadelphia, PA.
  7. Coluzzi F, Berti M. Change Pain: changing the approach to chronic pain. Minerva Med. 2011;102(4):289-307.
  8. Costigan M, Scholz J, Woolf CJ. Neuropathic pain: a maladaptive response of the nervous system to damage. Annu Rev Neurosci. 2009;32:1-32.
  9. Vorobeychik Y, Gordin V, Mao J, Chen L. Combination therapy for neuropathic pain: a review of current evidence. CNS Drugs. 2011;25(12):1023-1034.
  10. Lu R, Kallenborn-Gerhardt W, Geisslinger G, Schmidtko A. Additive antinociceptive effects of a combination of vitamin C and vitamin E after peripheral nerve injury. PLoS One. 2011;6(12):e29240. Epub 2011 Dec 14.
  11. Wang ZB, Song XJ, et al. Treatment of Pain and Hyperalgesia Due to Sensory Neuron Injury Using B-Vitamins in the Rat, J Neurophysiol 1999;82:3359-3370
  12. Caram-Salas NL, Reyes-Garcia G, Medina-Santillan R, Granados-Soto V. Thiamine and cyanocobalamin relieve neuropathic pain in rats: synergy with dexamethasone. Pharmacology. 2006;77(2):53-62.
  13. Koike H, Watanabe H, Inukai A, et al. Myopathy in thiamine deficiency: analysis of a case. J Neurol Sci. 2006;249(2):175-179.
  14. Ponce-Monter HA, Ortiz MI, Garza-Hernandez AF, et al. Effect of diclofenac with B vitamins on the treatment of acute pain originated by lower-limb fracture and surgery. Pain Res Treat. 2012;104782:31.
  15. Rosa KA, Gadotti VM, Rosa AO, Rodrigues AL, Calixto JB, Santos AR. Evidence for the involvement of glutamatergic system in the antinociceptive effect of ascorbic acid. Neurosci Lett. 2005;381(1-2):185-188.
  16. Carr AC, McCall C, The role of vitamin C in the treatment of pain: new insights, J TRansl Med. 2017;15:77-
  17. Besse JL, Gadeyne S, Galand-Desme S, Lerat JL, Moyen B. Effect of vitamin C on prevention of complex regional pain syndrome type I in foot and ankle surgery. Foot Ankle Surg. 2009;15(4):179-182.
  18. Na HS, Ryu JH, Do SH, The role of magnesium in pain,  In: Vink R, Nechifor M, editors. Magnesium in the Central Nervous System (Internet). Adelaide (AU): University of Adelaide Press; 2011
  19. Morris ME. Brain and CSF magnesium concentrations during magnesium deficit in animals and humans: neurological symptoms. Magnes Res. 1992 Dec;5(4):303-13.
  20. Gazirolu M, Celik O, Uguz AC, et al,  et al, Protective effects of riboflavin and selenium on brain microsomal Ca2+-ATPase and oxidative damage caused by glyceryl trinitrate in a rate headache model., Biol Trace Elem Res, March 2015, 164 (1) 72-79
  21. Nozaki C, Vergnano AM, Filliol D, et al, Zinc alleviates pain through high-affinity binding to the NMDA receptor NR2A subunit., Nat Neurosci. 2011 Jul 3: 14(8):1017-22.
  22. Andrade VS, Rojas DB, de Andrade RB, et al, A Possible Anti-Inflammatory Effect of Proline in the Brain Cortex and Cerebellum of Rats, Mol Neurobiol. 2018 May;55(5);4068-4077
  23. Selfridge NJ. Vitamin D and Pain: Making Sense of It All. Alternative Medicine Alert. 2010;13(7):77-78.
  24. Lasco A, Catalano A, Benvenga S. Improvement of primary dysmenorrhea caused by a single oral dose of vitamin D: results of a randomized, double-blind, placebo-controlled study. Arch Intern Med. 2012 Feb 27;172(4):366-7.
  25. Garcia-Gimenez JL and Pallardo FV, Maintenance of glutathione levels and its importance in epigenetic regulation, Front Pharmacol. 2014;5:88
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